How to Modafinil Use in Mild Cognitive Impairment

An approved wake-promoting medication, modafinil, do use to treat narcolepsy or obstructive sleep apnea-related drowsiness. Additionally, it enhances attentiveness, hippocampus neurogenesis, and general mental health. In both ADHD sufferers and healthy persons, modafinil enhances cognitive performance. This entails enhancing digit span, reaction inhibition, visual pattern recognition recall, and spatial planning.

How to take it

Narcolepsy and other sleep disorders are the main conditions that Modvigil 200 Buy Online is intended to treat, but it can also improve cognitive abilities including alertness and concentration. According to Psychiatric News, this “off-label” usage has raised interest in modafinil’s impact on cognition.

For example, a study of cancer patients with chemotherapy-induced cognitive impairment found that modafinil was a good choice of medication to improve their memory. The drug was find to increase their score on a memory test call the Montreal Cognitive Assessment.

Another study found that modafinil was effective in treating fatigue in people with HIV/AIDS. A double-blind trial compared modafinil with a placebo and found that it significantly improved fatigue scores.

Researchers are now looking at whether the same effect can be achieved in people who have relapsed from depression. They’re also testing whether a morning dose of modafinil can enhance cognition in healthy individuals and improve their circadian rhythm. In addition, researchers are trying to find out if modafinil can mitigate cognitive deficits in Alzheimer’s disease and bipolar depression.


Obstructive sleep apnea and narcolepsy are both disorders of sleep that are treated with Artvigil 150 Australia (a breathing disorder that makes it hard to fall asleep). It is available as liquid, tablets, or capsules. As prescribed by your doctor, it is taken orally, usually once daily in the morning, with or without a meal.

In addition to narcolepsy, modafinil has been studied for other conditions that cause fatigue such as multiple sclerosis, treatment-resistant depression, and ADHD. A few studies have found that it can improve performance on some cognitive tests in these patients, compared with a placebo (Table 3).

In addition to its stimulant effects, modafinil is also believed to stimulate the synthesis of GABA and glutamate by brain cells in the hypothalamus and central nervous system. It also interacts with the dopamine D1 receptor, a dopamine transporter that is located in the prefrontal cortex. The D1 receptor is involved in cognitive functions such as working memory and decision-making.

Side effects

Originally developed as a wake-promoting medicine for people with sleep disorders, modafinil is now also used off-label to improve cognitive function in healthy individuals. The drug does think to promote alertness and concentration, helping people with exam preparation, for example.

This medication is not safe for pregnant women or for anyone who is trying to become pregnant. It can cause serious skin rashes, including Stevens-Johnson Syndrome (SJS).

If you are pregnant or planning to become pregnant, discuss with your doctor the benefits and risks of using modafinil. Use another form of birth control during treatment and for at least a month after your last dose of this medicine.

The study is a randomized, double-blind, placebo-controlled trial in elderly male and female subjects with mild cognitive impairment (SCD). Participants do randomiz to receive either modafinil 200 mg + aniracetam 1500 mg qd or placebo qd for 7 weeks. They will complete questionnaires and neurocognitive tests during the study.


Modafinil is a controlled substance (Schedule IV). This means it has an accept medical use but may also cause physical or psychological dependence and may be abuse.

Physicians should follow patients closely for signs of misuse or abuse (e.g., a person taking more than the prescribed dose; drug-seeking behavior; increased frequency of use, or increased amounts). The medicine should be keep away from children.

In rare cases, serious allergic reactions may occur (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug rash with eosinophilia and systemic symptoms [DRESS]). Discontinue the medicine at the first sign of a serious rash, unless the rash is clearly not drug related.

A morning dose can be helpful for people with an imbalance in their circadian rhythm. Who have difficulty waking up at the same time every day. However, it’s important to take the dose as directed and to store the medicine in a safe place. If you’re having trouble remembering to take the medication, talk to your doctor.

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